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Cellect, Inc. signed a contract with the National Cancer Institute (NCI) for the identification of synthetic genes Lethal Breast Cancer
0Mountain View, CA (openPR) 30 September 2010 –
Cellect, Inc., a contract service provider that specializes in biotechnology to identify genetic screening for new therapeutic targets, has a contract for nine months with the National Cancer Institute (NCI) in technology companies RNAi use screening to identify synthetic lethal gene in breast cancer cells.
is considerable interest in cancer research is to identify and use combinations of genes that do not individually disrupted in cancer cells, but the combined results of suppression of cell death. This synergistic effect of block two genes is the basis for the development of new classes of therapies with low toxicity. However, approaching the complexity of these combinatorial interactions that make them particularly difficult to identify by screening dressed. Cellect test with pooled shRNA Lentiviral Libraries suppressor gene that can be easily adapted to combinatorial screens provide a unique approach to the practices of this synthetic lethal genetic interactions identified.
“We are very pleased to start this project and already have several hundred to several DNA damage repair genes and we selected in this screening test,” said CEO Dr. Alex Cellect Chenchik. “If successful, this will be the first approach for an effective screening hundreds of genes potentially interesting new synthetic lethal targets to discover cancer drugs. Once established, we will find with this combinatorial approach shRNA screening use the bank synthetic targets deadly in any form of cancer models, including prostate tumors and leukemic cell lines, with a set of genes. “
completion of the project, expected to synthetic lethality Cellect tract for a unique collection of isogenic strains from patient breast cancer cells by our staff, Dr. Sun Peiqing at the Scripps Research Institute provided derived built (TSRI). The models will be directly testable in animal models of ex vivo mouse xenographical for clinical effectiveness in monitoring the trials.
This project is part of a series of studies and cooperation Cellect is a worthwhile goal, a database of standard reference gene functional activities and therapeutic targets to develop. The approach for this first project synthetic lethality screening to be used directly applicable to other types of cancer in future studies, such as leukemia and prostate cancer cell lines.
About
Cellect, Inc.
Cellect (www.cellecta.com) is a private research contract, which provides high throughput (HT) RNAi-based genetic tests for the discovery and functional characterization of novel therapeutic targets are available. With its unique platform of lentiviral shRNA, HT sequencing and bioinformatics technologies, they offer the shRNA library screening and sequencing of lentiviral shRNA Libraries HT-pooling and journalists stable overexpression or knockdown cell lines. Cellect scientists have developed some of the most advanced technologies in collaboration with opinion leaders and funded by 11 NIH SBIR grants. For more information, visit www.cellecta.com, call 1-877-938-3910, or e-mail info@cellecta.com.
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Improving the security of explosives and identification
01 year ago
by admin
in Home Safety
Boca Raton, Florida (openPR) 28 August 2006
In response to the global demand for the identification, quantification and analysis of explosives, pesticides and other chemicals, announced ESRA Consulting Corporation, Boca Raton, FL, today announced the creation of explosives ID. The new division complements Esraa? S successful training programs in the transportation of explosives and commitment to the transportation infrastructure and the strengthening of security.
ID explosives offers programs for the national government and international airlines, law enforcement, maritime, military, public safety, railway transport, training, transportation and agencies, among others.
For more information on explosives ID, sign up http://www.idexplosives.com.
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Building Security
The Truth About Termite Identification
01 year ago
by admin
in Yard and Garden
Termite identification takes more than simply knowing the different members of the termite colony. There are a couple other things that every homeowner should know about if they are to protect their homes effectively against termites.
The Truth About Termites
The most common look that termites are usually associated with is the worker termites look. These are the termites that do all the food foraging and are creamy white in color. The truth though is that termites usually avoid the light and the open air.
Termites burrow deep in your soil and work its way to the wooden parts of your house through mud tunnels. This means that the damage to your property may also be undetected until there is already too much damage. Some homeowners do not know they have termites until damaged wood breaks off to reveal the white workers. The key to early termite identification is to look for tell tale signs of their presence.
Swarmer Termite Identification
Swarmers are the ones entrusted with the task of flying off to build new termite communities. Early termite identification therefore begins by looking for flying winged insects of a dark color, with straight bodies and four equal length wings that they might discard around your property. . These swarmers may fly to or away from your house.
Be especially watchful during the beginning of spring or after some rainfall. Although some may say that some swarmers simply get blown accidentally to your house, they might just establish a colony if the conditions are right.
Termite Identification Through Mud Tunnels
Mud tubes and tunnels are often a good aid for termite identification. Since worker termites try to avoid open spaces and day light, they usually move from their underground colony home to your house through mud tunnels. You should therefore be a little worried if you notice some seemingly dried mud that seem to rise up from the soil and stick on cracks or boards. When prodded, these tunnels may come off as grainy particles on your fingers. Some conditions are just so perfect for termites that they may even build mud mounds somewhere in your property.
Termite Identification Through Damage
If termites remain undetected for a long time, your home may already be in severe damage. Some signs of termite damage would be holes on the surface of the wood, paint cracks or wood that sounds hollow. Extensive termite damage may result in wood surface that easily breaks off when you prod it, revealing irregular sized hollow areas inside that may have traces of grainy mud.
Favorable Conditions
Although environmental conditions are not necessary for termite identification, there are some favorable conditions however that will attract potential colonists. You may for example have moist soil with wood contact on the ground. Ground termites love moist soil and the proximity of the wood to the soil may make their food harvesting work easier. Pipes that leak on wooden trash around the house and foundation cracks may also encourage termite infestation.
The primary step in do it yourself termite protection lies in your knowledge for termite identification. Know how to save your home from termites!
Mars Data Radio Frequency Identification (RFID) inventory tracking system for Party Linens
01 year ago
by admin
in Kitchen Products
Learn how Datamars RFID-based inventory tracking system helps La Tavola byssus track car rental inventory, manage costs and offer an excellent service. You’ll see how Datamars RFID works in a linen rental agreement, including outbound clean sheets, bound in linen and soiled linen, which are in the process. Plus interviews see how the RFID technology has helped to improve La Tavola inventory management and control costs.
Termite Identification: What a Termite Looks Like
01 year ago
by admin
in Yard and Garden
Both carpenter ants and worker termites can do damage to your furniture and home. Identifying which is which however is important for you to get the right help and treatment. Although a specialist normally knows what a termite looks like, your early detection can help provide immediate and proper attention.
A Subterranean Termites
Not everyone knows what a subterranean termite looks like but it is important to know exactly what they look like because they can cause serious damage to your home. There are many different species of termites which may further muddle your idea of how a termite looks like. Subterranean termites however are the most common species found in homes. They usually feed on wood and paper based products and to the unaware, every termite looks like it can harm your precious library or furniture. Your major concern however should be the worker termites.
A termite colony can be composed of several groups: soldier termites, swarmers or reproductives and worker termites. Not every termite looks like a grain of rice but a lot of them do. Soldiers however have mandibles while reproductives have wings. The worker termite looks like a reproductive but is smaller and has no wings. They are the most numerous in a colony and are the main wood eaters.
Swarmer Ants and Termites
The presence of swarmer termites is usually one of the first signs that there may be a termite infestation in your home. This is because swarmers are the ones who propagate termite colonies. Some think that a swarmer termite looks like a flying ant. The truth is that there are major differences.
An ant’s body is composed of a head, a slim abdomen and a thorax. A termite looks like it only has a head and a straight body.
As far as looks are concerned, both termites and ants share the same number of wings: four. Ants however have longer front than rear wings and have apparent vein marks. Termites have four wings of equal length that are far longer than the body and do not have vein marks.
Ants also have slightly bent antennae that may end in some sort of a small club. Termites on the other hand have beaded antennae that do not bend and have no club-like ends and point away from the body.
Where Swarmers Stay
There is no need for much concern if you find swarmers outside your house. These swarmers may just possibly be blown with the wind. Swarmers are also not the main termite wood eaters. You should be a little concerned though if you notice a number of swarmer ants flying away from your house and from cracks, windows and woodwork. You may have some form of termite infestation.
Getting Help
Termites are notoriously difficult to get rid of. Extensive infestations may not be effectively and safely treated by just gas or ordinary insect spray. You may have to ask for some expert help. Experts may use chemical treatment in which termicide is applied on wood and other house areas to prevent termites from invading the house structure. The baiting technique may also be used in which chemicals are spread throughout the colony through wood baits carrying chemicals.
Discover what a termite looks like. It may just save your home and property! Hire the best termite control company nearest you.
